Work

Automatic annotation of organellar genomes with DOGMA

Year: 2004

Type: article

Abstract: Summary: The Dual Organellar GenoMe Annotator (DOGMA) automates the annotation of organellar (plant chloroplast and animal mitochondrial) genomes. It is a Web-based package that allows the use of BLAST searches against a custom database, and conservation of basepairing in the secondary structure of animal mitochondrial tRNAs to identify and annotate genes. DOGMA provides a graphical user interface for viewing and editing annotations. Annotations are stored on our password-protected server to enable repeated sessions of working on the same genome. Finished annotations can be extracted for direct submission to GenBank. Availability: http://phylocluster.biosci.utexas.edu/dogma/ Supplementary information: Detailed documentation and tutorials for annotating both animal mitochondrial and plant chloroplast genomes can be found on the DOGMA home page.

Source: Bioinformatics

DOI: 10.1093/bioinformatics/bth352

Authors: Stacia K. Wyman, Robert K. Jansen, Jeffrey L. Boore

Institutions: The University of Texas at Austin, Joint Genome Institute

Language: English

Topic: Genomics and Phylogenetic Studies

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: National Science Foundation, U.S. Department of Energy, Biological and Environmental Research, Lawrence Berkeley National Laboratory