Work

Efficient Protiodesilylation of Unactivated C(sp3)−SiMe2Ph Bonds Using Tetrabutylammonium Fluoride

Year: 2005

Type: article

Abstract: [reaction: see text] The protiodesilylation of unactivated C(sp3)-SiMe2Ph bonds proceeds efficiently by treatment with tetrabutylammonium fluoride in wet DMF or THF via isolable dimethylsilanol intermediates.

Source: Organic Letters

DOI: 10.1021/ol0506821

Authors: Cheryl L. Heitzman, William T. Lambert, Eric Mertz, J. Brad Shotwell, Jennifer M. Tinsley, Porino Va, William R. Roush

Institution: University of Michigan

Language: English

Topic: Organoboron and organosilicon chemistry

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Cancer Institute, National Institute of General Medical Sciences

Awards: G2541790809, G4228851906, G5025541203, G5030439321, Synthesis of Angelmicin B, Synthesis of the Anti-tumor Marcrolide Amphidinolide C, G7489803701, SYNTHESIS OF POLYHDROXYLATED NATURAL PRODUCTS

OpenAlex ID: W2147130827

FWCI: 4.983

Cites: 23

Cited by: 50

Related to: 10