Work

Staphylococcus aureus YoeB Homologues Inhibit Translation Initiation

Year: 2009

Type: article

Abstract: YoeB is a bacterial toxin encoded by the yefM-yoeB toxin-antitoxin system found in various bacterial genomes. Here, we show that Staphylococcus aureus contains two YoeB homologues, both of which function as ribosome-dependent mRNA interferases to inhibit translation initiation in a manner identical to that of YoeB-ec from Escherichia coli.

Source: Journal of Bacteriology

DOI: 10.1128/jb.00623-09

Authors: Satoshi Yoshizumi, Yonglong Zhang, Yoshihiro Yamaguchi, Liang Chen, Barry N. Kreiswirth, Masayori Inouye

Institutions: Rutgers, The State University of New Jersey, International Center for Public Health

Language: English

Topic: Bacterial Genetics and Biotechnology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences