Year: 2004
Type: article
Abstract: Cotton PB, Durkalski VL, Pineau BC, et al . Computed tomographic colonography (virtual colonoscopy): a multicenter comparison with standard colonoscopy for detection of colorectal neoplasia. JAMA 2004;291:1713–9. [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] Q In patients presenting for colonoscopy, what is the accuracy of computed tomographic (CT) colonoscopy (virtual colonoscopy [VC]) in detecting colororectal neoplasia? Clinical impact ratings GP/FP/Primary care ★★★★☆☆☆ IM/Ambulatory care ★★★★★★☆ Gastroenterology ★★★★★☆☆ ### ![Graphic][5] Design: blinded, non-inferiority comparison of VC with conventional colonoscopy. ### ![Graphic][6] Setting: 8 clinical centres in the US and 1 centre in the UK. ### ![Graphic][7] Patients: 615 patients (mean age 61 y, 55% women) presenting for colonoscopy because of overt and occult rectal bleeding, change in stool habit, abdominal pain, or surveillance after polypectomy. Patients who had had colonoscopy within the past 3 years were excluded. ### ![Graphic][8] Description of tests: the colon was insufflated with room air or carbon dioxide. VC was done using 2 and 4 section CT scanners with nominal slice thicknesses of 2.5 or 5 mm and reconstruction increments of 1.5 or 1 mm, depending on equipment. Scans were read in 2 dimensional slices and 3 dimensional snapshot reconstructions when necessary. Radiologist interpretations were recorded in a sealed envelope for each colon segment. Conventional colonoscopy was done within 2 hours of VC. Endoscopists were blinded … [1]: {openurl}?query=rft.jtitle%253DJAMA%26rft.stitle%253DJAMA%26rft.issn%253D0002-9955%26rft.aulast%253DCotton%26rft.auinit1%253DP.%2BB.%26rft.volume%253D291%26rft.issue%253D14%26rft.spage%253D1713%26rft.epage%253D1719%26rft.atitle%253DComputed%2BTomographic%2BColonography%2B%2528Virtual%2BColonoscopy%2529%253A%2BA%2BMulticenter%2BComparison%2BWith%2BStandard%2BColonoscopy%2Bfor%2BDetection%2Bof%2BColorectal%2BNeoplasia%26rft_id%253Dinfo%253Adoi%252F10.1001%252Fjama.291.14.1713%26rft_id%253Dinfo%253Apmid%252F15082698%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1001/jama.291.14.1713&link_type=DOI [3]: /lookup/external-ref?access_num=15082698&link_type=MED&atom=%2Febmed%2F9%2F4%2F122.atom [4]: /lookup/external-ref?access_num=000220788700028&link_type=ISI [5]: /embed/inline-graphic-1.gif [6]: /embed/inline-graphic-2.gif [7]: /embed/inline-graphic-3.gif [8]: /embed/inline-graphic-4.gif
Source: BMJ Evidence-Based Medicine
DOI: 10.1136/ebm.9.4.122
Author: R. H Fletcher
Institution: Harvard University
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2148546958