Year: 2014
Type: review
Abstract: Various strategies for ocular drug delivery are considered; from basic formulation techniques for improving availability of drugs; viscosity enhancers and mucoadhesives aid drug retention and penetration enhancers promote drug transport into the eye. The use of drug-loaded contact lenses and ocular inserts allows drugs to be better placed where they are needed for more direct delivery. Developments in ocular implants gives a means to overcome the physical barriers that traditionally prevented effective treatment. Implant technologies are under development allowing long-term drug delivery from a single procedure, these devices allow posterior chamber diseases to be effectively treated. Future developments could bring artificial corneas to eliminate the need for donor tissue and one-off implantable drug depots lasting the patient's lifetime.
Source: Therapeutic Delivery
DOI: 10.4155/tde.14.75
Institution: University of Reading
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: bronze
Estimated APC paid: $2,974
Award: Doctoral Training Grant
OpenAlex ID: W2148638984