Work

Clinical management of a patient with drug dependence who attempted suicide while receiving peginterferon therapy for chronic hepatitis C

Year: 2009

Type: article

Abstract: Pegylated interferon-alpha combined with ribavirin is the current gold standard treatment for chronic hepatitis C. Illicit drug dependence is not a rare co-morbidity among chronic hepatitis C population, what can make antiviral treatment an outmost challenge. Despite high sustained virological response rate following antiviral treatment, serious psychiatric adverse reactions may occur, like depression and suicide attempt. We report a patient with recurrent depressive disorder, previous history of suicide attempt and illicit drug dependence. We discuss the singularities and challenges of managing this patient in order to complete the antiviral treatment.

Source: The Brazilian Journal of Infectious Diseases

DOI: 10.1590/s1413-86702009000500015

Authors: Bruno Cópio Fábregas, Alexandre Sampaio Moura, Renata Cristiane Marciano, Ricardo Andrade Carmo, Antônio Lúcio Teixeira

Institution: Universidade Federal de Minas Gerais

Language: English

Topic: Hepatitis C virus research

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,600