Work

Single Chemical Modifications of the C-1027 Enediyne Core, a Radiomimetic Antitumor Drug, Affect Both Drug Potency and the Role of Ataxia-Telangiectasia Mutated in Cellular Responses to DNA Double-Strand Breaks

Year: 2007

Type: article

Source: Cancer Research

DOI: 10.1158/0008-5472.can-06-2893

Authors: Daniel R. Kennedy, Loretta S. Gawron, Jianhua Ju, Wen Liu, Ben Shen, Terry A. Beerman

Institutions: Roswell Park Comprehensive Cancer Center, University of Wisconsin–Madison

Language: English

Topic: DNA Repair Mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: National Cancer Institute

Awards: G168441794, UWCCC National Cooperative Drug Discovery Group for Can*, Enediyne Biosynthesis and Engineering, G2271657281, G2946770808, G3119682821, Cellular Responses to Cancer Drug-Induced Genomic Breaks, G7453756655, Roswell Park Cancer Center Support Grant

OpenAlex ID: W2149578037

FWCI: 2.344

Cites: 50

Cited by: 52

Related to: 10