Melanoma genome sequencing reveals frequent PREX2 mutations
Work
Year: 2012
Type: article
Abstract: Whole-genome sequencing of 25 metastatic melanomas and matched germline DNA in humans reveals that the highest mutation load is associated with chronic sun exposure, and that the PREX2 gene is mutated... more
Source: Nature
Authors Michael F. Berger, Eran Hodis, Timothy P. Heffernan, Yonathan Lissanu Deribe, Michael S. Lawrence +43 more
Institutions Broad Institute, Dana-Farber Cancer Institute, Essen University Hospital, Weizmann Institute of Science, Massachusetts General Hospital +4 more
Cites: 29
Cited by: 742
Related to: 10
FWCI: 41.35
Citation percentile (by year/subfield): 100
Topic: Melanoma and MAPK Pathways
Subfield: Molecular Biology
Domain: Life Sciences
Sustainable Development Goal Good health and well-being
Open Access status: hybrid
APC paid (est): $11,690