Work

Arterial Spin Labeling Blood Flow MRI: Its Role in the Early Characterization of Alzheimer's Disease

Year: 2010

Type: article

Abstract: Arterial spin labeling (ASL) enables the noninvasive, quantitative imaging of cerebral blood flow using standard magnetic resonance imaging (MRI) equipment. Because it requires no contrast injection, ASL can add resting functional information to MRI studies measuring atrophy and signs of ischemic injury. Key features of ASL technology that may affect studies in Alzheimer's disease are described. The existing literature describing ASL blood flow imaging applied to Alzheimer's disease and related dementia is reviewed, and the potential role of ASL in treatment and prevention studies of early Alzheimer's disease is discussed.

Source: Journal of Alzheimer s Disease

DOI: 10.3233/jad-2010-091699

Authors: David C. Alsop, Weiying Dai, Murray Grossman, John A. Detre

Institutions: Beth Israel Deaconess Medical Center, Harvard University, University of Pennsylvania

Language: English

Topic: Advanced MRI Techniques and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute on Aging