Work

Treatment Strategy for Non-Responders to PDE5 Inhibitors

Year: 2013

Type: article

Abstract: Currently, phosphodiesterase type 5 (PDE5) inhibitors are the initial treatment option for erectile dysfunction. The reported efficacy of PDE5 inhibitors is about 70%, although it is significantly lower in difficult-to-treat subpopulations. Treatment failures might be due to the severity of the underlying pathophysiology, improper use of medication, unrealistic patient expectations, difficult relationship dynamics, severe performance anxiety, and other psychological problems. Physicians must address these issues to identify true treatment failures attributable to the drugs. This article discusses factors that might affect the response to PDE5 inhibitors and develops a strategy to maximize the overall efficacy of PDE5 inhibitors in initial non-responders to PDE5 inhibitors.

Source: The World Journal of Men s Health

DOI: 10.5534/wjmh.2013.31.1.31

Authors: Nam Cheol Park, Tae Nam Kim, Hyun Jun Park

Institutions: Pusan National University Hospital, Pusan National University

Language: English

Topic: Sexual function and dysfunction studies

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Pusan National University, Pusan National University Hospital