Year: 2012
Type: article
Abstract: During the past few years, The Journal of Neuroscience has published more than 30 articles that describe investigations that used Diffusion Tensor Imaging (DTI) and related techniques as a primary observation method. This illustrates a growing interest in DTI within the basic and clinical neuroscience communities. This article summarizes DTI methodology in terms that can be immediately understood by the neuroscientist who has little previous exposure to DTI. It describes the fundamentals of water molecular diffusion coefficient measurement in brain tissue and illustrates how these fundamentals can be used to form vivid and useful depictions of white matter macroscopic and microscopic anatomy. It also describes current research applications and the technique's attributes and limitations. It is hoped that this article will help the readers of this Journal to more effectively evaluate neuroscience studies that use DTI.
Source: Journal of Neuroscience
Author: Jeffry R. Alger
Institution: University of California, Los Angeles
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Funders: National Institute of Mental Health, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Neurological Disorders and Stroke, National Institute of Biomedical Imaging and Bioengineering, Eunice Kennedy Shriver National Institute of Child Health and Human Development
Awards: Neuroimaging and Neurochemical Biomarkers in ADHD, Reconnection of Neural Networks and Cognitive Recovery after Pediatric TBI, Mechanisms Altering Electrical Conductivity & DTI in Epilepsy Surgery Patients, Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network Discovery Site, Cognitive-Behavioral Therapy & Glutametergic Neurometabolites in Pediatric OCD, UCLA SPOTRIAS CENTER APPLICATION RENEWAL-PROGRAM PROJECT, Partnership for MR Spectroscopic Imaging Data Processing
OpenAlex ID: W2150666445