Work

Regulation of DNA glycosylases and their role in limiting disease

Year: 2012

Type: review

Abstract: This review will present a current understanding of mechanisms for the initiation of base excision repair (BER) of oxidatively-induced DNA damage and the biological consequences of deficiencies in these enzymes in mouse model systems and human populations.

Source: Free Radical Research

DOI: 10.3109/10715762.2012.655730

Authors: Harini Sampath, Amanda K. McCullough, R. Stephen Lloyd

Institution: Oregon Health & Science University

Language: English

Topic: DNA Repair Mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases