Work

Cancer Therapy: Nucleus‐Targeting Gold Nanoclusters for Simultaneous In Vivo Fluorescence Imaging, Gene Delivery, and NIR‐Light Activated Photodynamic Therapy (Adv. Funct. Mater. 37/2015)

Year: 2015

Type: article

Abstract: Nucleus-targeting gold nanoclusters (TAT peptide-Au NCs) can act as intrinsic fluorescence probe for bioimaging, as shown by K. C. Hwang and co-workers on page 5934. The nanoclusters also sensitize formation of singlet oxygen upon NIR light activation, to exert effective photodynamic therapeutic effects in killing cancer cells via subsequent DNA damage inside the nucleus, without using any additional photosensitizers.

Source: Advanced Functional Materials

DOI: 10.1002/adfm.201570247

Authors: Raviraj Vankayala, Chien‐Lin Kuo, Karthik Nuthalapati, Chi‐Shiun Chiang, Kuo Chu Hwang

Institution: National Tsing Hua University

Language: English

Topic: Nanocluster Synthesis and Applications

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2151245451

FWCI: 0.27

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Cited by: 3

Related to: 10