Work

Current understanding of fungal microflora in inflammatory bowel disease pathogenesis

Year: 2008

Type: review

Abstract: Inflammatory bowel diseases are a current and growing public health problem, with a prevalence that appears to be increasing in most countries and cultures. While most research into the triggering phenomenon has focused on the interaction between commensal bacteria and inflammatory bowel disease, enteric fungi may also be important in determining disease susceptibility. Herein we review what is known about enteric fungi and the mechanisms by which they and their dysregulation might be involved in triggering inflammatory diseases of the bowel.

Source: Inflammatory Bowel Diseases

DOI: 10.1002/ibd.20402

Authors: David Underhill, Jonathan Braun

Institutions: Cedars-Sinai Medical Center, University of California, Los Angeles

Language: English

Topic: Inflammatory Bowel Disease

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: American Heart Association, National Institutes of Health, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases