Year: 2009
Type: dissertation
Abstract: The main objectives were to study the effect of frequently repeated supragingival plaque\nremoval on the subgingival microbiota and periodontal pocket reduction and to analyze the\nadjunctive effect of different antimicrobial agents on the treatment of periodontal disease.\nSubjects with gingivitis or chronic periodontitis were included.\nThe patients in Study I underwent professional supragingival removal of plaque and calculus\n2-3 times/week for 30 weeks. At sites with suprabony and infrabony pockets and furcation\nsites, repeated supragingival plaque removal reduced the total number of microorganisms, as\nwell as the percentage of sites with P. gingivalis.\nIn Study II, six months of unsupervised use of a dentifrice containing 0.3% magnolia extract\nproduced significantly less gingival inflammation than a corresponding control dentifrice.\nFurthermore, at sites with similar amounts of plaque, fewer signs of gingival inflammation\nwere observed in the magnolia group than the control group.\nIn Study III, the effect of topically applied PVP iodine used as an adjunct both during basic\nSRP and at re-treatment during long term-maintenance was studied. PVP iodine, applied\ntopically during subgingival instrumentation, may improve the outcome of SRP therapy.\nIn Study IV, the short- and long-term effects of the systemic administration of tetracycline in\nconjunction with SRP were studied. One year after active therapy, the probing attachment\nlevel in the test group was almost 3 times higher than in the control group. Re-examinations\nafter 3, 5 and 13 years of SPT disclosed that this short-term benefit was not maintained in the\nlonger perspective.\nIn Study V, the effects of topically applied minocycline in combination with surgery on PPD\nreduction were analyzed. Local minocycline as an adjunct to surgery produced a statistically\nsignificantly larger reduction in probing depth (0.3mm) compared with surgery alone.
Author: M.‐K. Hellström
Language: English
Subfield: Periodontics
Field: Dentistry
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2151641733