Real-Time PCR detection and quantitation of Helicobacter pylori clarithromycin-resistant strains in archival material and correlation with Sydney classification.
Year: 2013
Type: article
Study design: Observational Study
Abstract: BACKGROUND: (+) patients that lead to clarithromycin resistance and to correlate them with histology data. METHODS: (+) gastritis was done according to the Sydney criteria. Genetic material was analyzed with the ClariRes™ RT-PCR bi-probe based assay for the determination of point mutations in the 23S rRNA gene and with a Quantitative-RT-PCR (Q-RT-PCR) method for the quantitation of RESULTS: density as histologically determined. CONCLUSION: genome that affect susceptibility to clarithromycin correlate with histological features of gastritis.
Source: Europe PMC (PubMed Central)
Institutions: NIMTS Hospital, University of Ioannina, Henry Dunant Hospital
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2152865102