Work

Impact of Comorbidities on Ischemic Stroke Outcomes in Women

Year: 2008

Type: article

Abstract: BACKGROUND AND PURPOSE: We assessed the association of prestroke comorbidities with long-term stroke outcomes among women with ischemic stroke. METHODS: Prestroke comorbid conditions in 133 women admitted with acute ischemic stroke were scored with the Charlson Index (CI). We assessed whether the CI and other specific conditions were associated with modified Rankin Score (mRS) at 90 days or more poststroke. RESULTS: After adjustment for initial NIHSS and age, higher CI was the sole factor independently associated with poorer 90 day mRS scores. When CI was excluded, coronary disease and diabetes were independently associated with poorer outcome. CONCLUSIONS: The extent of comorbidities as assessed by the CI is independently associated with 90-day mRS among women with ischemic stroke, but the individual comorbidities of CHD and DM were each associated with functional outcome.

Source: Stroke

DOI: 10.1161/strokeaha.107.509281

Authors: Cheryl D. Bushnell, Jeanne Lee, Pamela W. Duncan, L. Kristin Newby, Larry B. Goldstein

Institutions: Duke University, Duke Medical Center, Duke Clinical Research Institute

Language: English

Topic: Acute Ischemic Stroke Management

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Institute of Neurological Disorders and Stroke