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Alternate Method for the Synthesis of Six-Membered Carbocycles with Five Stereocenters: 1,2,3,4,6-Pentasubstituted-4-hydroxy-cyclohexanes

Year: 2015

Type: article

Abstract: A series of novel 1,2,3,4,6-pentasubstituted-4-hydroxy-cyclohexanes (3a–u) were synthesized from the reaction of aromatic ketones with aromatic aldehydes under mild reaction conditions in good yields. The stereochemistry of the synthesized compounds was established using 1D and 2D-NMR spectra.

Source: Synthetic Communications

DOI: 10.1080/00397911.2015.1080845

Authors: Hayreddin Gezegen, Mustafa Ceylan

Institutions: Sivas Cumhuriyet Üniversitesi, Tokat Gaziosmanpaşa Üniversitesi

Language: English

Topic: Asymmetric Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W2153071895

FWCI: 0.565

Cites: 20

Cited by: 9

Related to: 10