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Lapatinib and Obatoclax Kill Tumor Cells through Blockade of ERBB1/3/4 and through Inhibition of BCL-xL and MCL-1

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Year: 2012
Type: article
Source: Molecular Pharmacology
DOI: 10.1124/mol.112.077586
Authors: Nichola Cruickshanks, Hossein A. Hamed, M. Danielle Bareford, Andrew Poklepovic, Paul B. Fisher, Steven Grant, Paul Dent
Institution: Virginia Commonwealth University
Language: English

Topic: Cell death mechanisms and regulation
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: U.S. Department of Defense, National Institutes of Health, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases
Awards: G169079229, G1805530462, G2447325627, G2953226657, G3595794522, Signaling Pathways Regulating Epithelial Cell Survival, Pancreatic Cancer Management by Novel Gene Therapy & Dietary Agents, OSU-03012 therapy for glioblastoma, G6986738744, COMBINED INHIBITION OF CHK1 AND MEK1/2 LEADS TO TUMOR CELL DEATH IN VIVO, MDA-7: Novel Cancer Therapeutic Gene, G9000057114
OpenAlex ID: W2153215028
FWCI: 1.742
Cites: 46
Cited by: 24
Related to: 10
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