Work

Late Pneumocystis Pneumonia After HSCT: Atypical Presentation and Lack of Correlation with CD4 Count

Year: 2013

Type: article

Abstract: Duration of Pneumocystis pneumonia (PCP) prophylaxis after allogeneic HSCT is not well defined. Guidelines recommend at least six months, and longer for patients on immunosuppression. We report six cases of PCP that happened late after allo-HSCT (median 36 months, range 19-80). All had received peripheral blood HSCT: three from matched sibling donors (MRD), and three from matched unrelated donors (MUD) (the latter with alemtuzumab conditioning). At the time of PCP, three patients (#3, #4, #5) were not on immunosuppression and had no active graft versus host disease (GVHD).

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2012.11.260