Host Range of Chlamydiaphages φCPAR39 and Chp3
Year: 2003
Type: article
Abstract: The host range of phiCPAR39 is limited to four Chlamydophila species: C. abortus, C. caviae, C. pecorum, and C. pneumoniae. Chp3 (a newly discovered bacteriophage isolated from C. pecorum) shares three of these hosts (C. abortus, C. caviae, and C. pecorum) but can additionally infect Chlamydophila felis. The ability to support replication was directly correlated with the binding properties of the respective bacteriophages with their host species. Binding studies also show that phiCPAR39 and Chp3 use different host receptors to infect the same host cells: cell binding is sensitive to proteinase K treatment, confirming that the chlamydiaphage receptors are proteinaceous in nature.
Source: Journal of Bacteriology
Authors: J. S. Everson, S. A. Garner, P. R. Lambden, B. A Fane, I. N. Clarke
Institutions: Southampton General Hospital, University of Arizona
Language: English
Subfield: Ecology
Field: Environmental Science
Domain: Physical Sciences
Open Access status: green
Funder: Wellcome Trust
OpenAlex ID: W2153808955