Work

High resolution two-dimensional electrophoresis of human plasma proteins.

Year: 1977

Type: article

Abstract: The two-dimensional electrophoretic technique of O'Farrell has been adapted to the analysis of human plasma proteins, and 30 polypeptides have been identified in the pattern produced. Genetic variants involving charge (isoelectric point) or size (molecular weight in the presence of sodium dodecyl sulfate) changes should be routinely detectable in at least 20 proteins at once, facilitating studies of human mutation rates.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.74.12.5421

Authors: L Anderson, N G Anderson

Language: English

Topic: Advanced Proteomics Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W2154798437

FWCI: 13.39

Cites: 22

Cited by: 653

Related to: 10