Work

Enantioselective, Copper( I )‐Catalyzed Three‐Component Reaction for the Preparation of Propargylamines

Year: 2003

Type: article

Abstract: The one-pot reaction of alkynes, aldehydes, and secondary amines in the presence of CuBr/quinap as the catalytic system provides various enantiomerically enriched propargylamines in good yields (up to 99 %) and good selectivities (up to 96 % ee) [Eq. (1)].

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.200352578

Authors: Nina Gommermann, Christopher Koradin, Kurt Polborn, Paul Knochel

Institution: Ludwig-Maximilians-Universität München

Language: English

Topic: Catalytic Alkyne Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

OpenAlex ID: W2154929030

FWCI: 12.3

Cites: 42

Cited by: 469

Related to: 10