Work

Label-free in vivo optical imaging of microvasculature and oxygenation level

Year: 2008

Type: article

Abstract: The ability to perform high-resolution imaging of microvasculature and its oxygenation is very important in studying early tumor development. Toward this goal, we improved upon our excited state absorption (ESA)-based imaging technique to allow us to not only image hemoglobin directly but also differentiate between oxy- and deoxyhemoglobin in tissue. We demonstrate the separation of arterioles from venules in a live nude mouse ear using our imaging technique.

Source: Journal of Biomedical Optics

DOI: 10.1117/1.2968260

Authors: Dan Fu, Thomas E. Matthews, Tong Ye, Ivan Piletic, Warren S. Warren

Institutions: Duke University, University of Alabama at Birmingham, Stanford University

Language: English

Topic: Optical Imaging and Spectroscopy Techniques

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2155592988