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Inside Back Cover: A Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase Pair (Angew. Chem. Int. Ed. 34/2015)

Year: 2015

Type: article

Abstract: With added nucleotide “letters” nucleic acids can be incorporated into RNA in a functional form. In their Communication on page 9853 ff, the Piccirilli and Benner groups joined to deliver the first molecular structure (symbolized by the “photographs” in the picture) of a functional RNA molecule built from a six nucleotide alphabet (G, A, U, C, and the artificial nucleotides Z and P).

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.201506280

Authors: Armando R. Hernandez, Yaming Shao, Shuichi Hoshika, Zunyi Yang, Sandip A. Shelke, Julien Herrou, Hyo‐Joong Kim, Myong‐Jung Kim, Joseph A. Piccirilli, Steven A. Benner

Institutions: University of Chicago, Firebird Biomolecular Sciences (United States), Foundation for Applied Molecular Evolution

Language: English

Topic: RNA and protein synthesis mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W2155804778

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