Work

Commentary: Update on Animal Models for NTP Studies

Year: 2009

Type: editorial

Abstract: Based on recommendations of participants at the National Toxicology Program (NTP) workshop "Animal Models for the NTP Cancer Bioassay: Strains and Stocks-Should We Switch?" some modifications to the NTP rodent cancer bioassay were made. The B6C3F1 remains the mouse model used in the cancer bioassay. The use of multiple strains of mice will be explored through a new branch within the NTP, the Host Susceptibility Branch. Several rat models were evaluated; the Harlan Sprague Dawley rat is currently being used in the NTP studies.

Source: Toxicologic Pathology

DOI: 10.1177/0192623309356450

Authors: Angela P. King-Herbert, Robert C. Sills, John R. Bucher

Institutions: National Institute of Environmental Health Sciences, National Institutes of Health

Language: English

Topic: Carcinogens and Genotoxicity Assessment

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: National Institutes of Health

OpenAlex ID: W2155830966

Cites: 4

Cited by: 48

Related to: 10