Work

Phosphorescent Nanoscale Coordination Polymers as Contrast Agents for Optical Imaging

Year: 2011

Type: article

Abstract: Seeing is believing: Phosphorescent nanoscale coordination polymers (NCPs) with unprecedentedly high dye loadings were coated with thin silica shells to tune the dye release kinetics (see picture). Further functionalization of the NCP/silica particles with poly(ethylene glycol) (PEG) and PEG-anisamide enhanced their biocompatibility and targeting ability, allowing cancer-specific imaging of human lung cancer H460 cells.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.201008277

Authors: Demin Liu, Rachel C. Huxford, Wenbin Lin

Institution: University of North Carolina at Chapel Hill

Language: English

Topic: Luminescence and Fluorescent Materials

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Cancer Institute