Work

Effects of treadmill running on extracellular basal levels of glutamate and GABA at dentate gyrus of streptozotocin-induced diabetic rats.

Year: 2010

Type: article

Abstract: BACKGROUND: The present study evaluated the effects of treadmill running on extracellular basal levels of glutamate and GABA at dentate gyrus of streptozotocin-induced diabetic rats. METHODS: After 12 weeks of diabetes induction and exercise period, extracellular levels of glutamate and GABA were investigated. RESULTS: The results showed that glutamate levels were significantly decreased in diabetes-rest group comparing to the control-rest and the diabetes-exercise groups. CONCLUSIONS: The findings support the possibility that treadmill running is helpful in alleviating neurotransmitter homeostasis and alterations in transmission in diabetes mellitus.

Source: Europe PMC (PubMed Central)

Authors: Parham Reisi, Hojjatallah Alaei, Shirin Babri, Mohammad Reza Sharifi, Gisue Mohaddes, Elaheh Soleimannejad, Bahman Rashidi

Institutions: Isfahan University of Medical Sciences, Tabriz University of Medical Sciences, Pasteur Institute of Iran

Language: English

Topic: Neuroscience and Neuropharmacology Research

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2155958145

FWCI: 0.226

Cites: 10

Cited by: 6

Related to: 10