Work

Cutaneous Squamous Cell Carcinoma: Defining the High-Risk Variant

Year: 2013

Type: article

Abstract: With a lifetime incidence of approximately 10% in the general population, cutaneous squamous cell carcinoma (CSCC) is the second most common type of nonmelanoma skin cancer. Most CSCCs are benign and can be completely eradicated by surgery or other dermatological procedures. There is, however, a subgroup associated with an increased likelihood of lymph node metastases and, therefore, with high morbidity and mortality. This article analyzes the various factors that define aggressive CSCC. We propose a method for defining high-risk SCC on the basis of a series of major and minor criteria. This method will allow better prognostic evaluation and enable personalized management of patients with high-risk SCC, possibly leading to improved overall survival.

Source: Actas Dermo-Sifiliográficas

DOI: 10.1016/j.adengl.2011.12.012

Authors: A. Martorell-Calatayud, O. Sanmartín Jimenez, J. Cruz Mojarrieta, C. Guillén Barona

Institutions: Hospital de Manises, Fundación Instituto Valenciano de Oncología

Language: English

Topic: Nonmelanoma Skin Cancer Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $2,080