Work

Transcription Activation by a Variety of AraC/XylS Family Activators Does Not Depend on the Class II-Specific Activation Determinant in the N-Terminal Domain of the RNA Polymerase Alpha Subunit

Year: 2000

Type: article

Abstract: The N-terminal domain of the RNA polymerase alpha subunit (alpha-NTD) was tested for a role in transcription activation by a variety of AraC/XylS family members. Based on substitutions at residues 162 to 165 and an extensive genetic screen we conclude that alpha-NTD is not an activation target for these activators.

Source: Journal of Bacteriology

DOI: 10.1128/jb.182.24.7075-7077.2000

Authors: Susan M. Egan, Andrew J. Pease, Jeffrey Lang, Xiang Li, Vydehi Rao, William K. Gillette, Raquel Ruiz, Juan L. Ramos, Richard E. Wolf

Institutions: University of Kansas, University of Maryland, Baltimore County, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Consejo Superior de Investigaciones Científicas, Estación Experimental del Zaidín

Language: English

Topic: Bacterial Genetics and Biotechnology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Awards: TRANSCRIPTION ACTIVATION AT THE RHABAD OPERON, G187195762, G1968582138, DNA Binding and Transcriptional Activation by SoxS, Transcription Activation at the rhaBAD Operon

OpenAlex ID: W2156108139

FWCI: 1.555

Cites: 32

Cited by: 21

Related to: 10