Work

Transplantation for AML in Children

Year: 2012

Type: article

Abstract: Jean Sanders and colleagues at the Fred Hutchinson Cancer Research Center reported in 1985 that sibling donor transplant in first remission is the optimal treatment for childhood acuty myelogenous leukemia (AML), with disease-free survival of 64%, and excellent quality of life [1]. This seminal observation remains largely, although not entirely, true 26 years later. Current movement in the application of transplant in AML is in 2 contrasting directions. Physicians are now withholding transplant from children with very good-risk disease, and trying to use transplant earlier in children with the highest risk disease.

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2011.10.035

Authors: Paul A. Carpenter, Soheil Meshinchi, Stella M. Davies

Institutions: University of Washington, Fred Hutch Cancer Center, Cincinnati Children's Hospital Medical Center

Language: English

Topic: Hematopoietic Stem Cell Transplantation

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,650