Work

STAT1 contributes to HLA class I upregulation and CTL reactivity after anti-EGFR mAb cetuximab therapy in head and neck cancer patients

Year: 2013

Type: article

Abstract: Meeting abstracts Squamous cell carcinoma of head and neck (HNSCC) cells express low HLA class I and antigen processing machinery (APM) components, such as transporter TAP-1/2, which is associated with the reduced sensitivity to cytotoxic T lymphocyte (CTL) mediated lysis. Epidermal growth factor

Source: Journal for ImmunoTherapy of Cancer

DOI: 10.1186/2051-1426-1-s1-p175

Authors: Raghvendra M Srivastava, Hyun-bae Jie, Soldano Ferrone, Robert L Ferris

Institutions: University of Pittsburgh, Harvard University, Massachusetts General Hospital

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,490