Work

Improved base calling for the Illumina Genome Analyzer using machine learning strategies

Year: 2009

Type: article

Abstract: The Illumina Genome Analyzer generates millions of short sequencing reads. We present Ibis (Improved base identification system), an accurate, fast and easy-to-use base caller that significantly reduces the error rate and increases the output of usable reads. Ibis is faster and more robust with respect to chemistry and technology than other publicly available packages. Ibis is freely available under the GPL from http://bioinf.eva.mpg.de/Ibis/.

Source: Genome biology

DOI: 10.1186/gb-2009-10-8-r83

Authors: Martin Kircher, Udo Stenzel, Janet Kelso

Institution: Max Planck Institute for Evolutionary Anthropology

Language: English

Topic: Genomics and Phylogenetic Studies

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $1,559

Funder: Max-Planck-Institut für Evolutionäre Anthropologie