Work

Effects of Aging on Inflammation and Hemostasis through the Continuum of Critical Illness.

Year: 2011

Type: article

Abstract: Older age has long been associated with altered inflammation and hemostasis regulation. Emerging evidence suggests that age-related differences in inflammation and hemostasis abnormalities may play a role in the development of and long-term outcomes after critical illness. A better understanding of underlying mechanisms may provide new possibilities for therapeutic interventions. In this review, we will examine how age-related differences in inflammatory and coagulation responses are affected through the continuum of healthy state, before infection occurs, to severe sepsis and recovery.

Source: Europe PMC (PubMed Central)

Authors: Sachin S Kale, Sachin Yende

Institutions: University of Pittsburgh, University of Pittsburgh Medical Center

Language: English

Topic: Sepsis Diagnosis and Treatment

Subfield: Critical Care and Intensive Care Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2156545191

FWCI: 2.97

Cites: 69

Cited by: 61

Related to: 10