Work

Circulating tumor DNA moves further into the spotlight

Year: 2014

Type: article

Abstract: Assessment of somatic genomic alterations from tumors can now be performed by sequencing circulating tumor DNA from the cell-free component of blood. This procedure, which identifies tumor-derived somatic mutations from a simple blood sample, circumvents the need for tumor tissue. A recent study highlights the promise of circulating tumor DNA to guide therapeutic decisions in a variety of solid tumors for both clinical and investigative purposes, as well as providing a tool for the early detection of cancer.

Source: Genome Medicine

DOI: 10.1186/gm552

Authors: Mark Sausen, Sonya Parpart, Luis A Diaz

Institutions: Howard Hughes Medical Institute, Johns Hopkins University, Sidney Kimmel Comprehensive Cancer Center

Language: English

Topic: Cancer Genomics and Diagnostics

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,290