Work

Effect of high-fat diets with different fatty acid composition on hepatic 11β-hydroxysteroid dehydrogenase type 1 activity in rats

Year: 2006

Type: article

Abstract: Recent studies suggest a key role for tissue aberrant expression of 1 Ip-hydroxysteroid dehydrogenase type 1 (1 Iβ-HSDl) and for tissue glucocorticoid excess in dysregulation of metabolism observed in diabetes and other metabolic disorders linked to central obesity. In an experiment carried out in 50 adult Wistar rats fed on diets containing sunflower oil, rapeseed oil, lard or cod liver oil at two levels (20 and 40% w/w), we were the first to show a beneficial inhibitory effect of all fats but one (sunflower oil) on hepatic 11β-HSD1 activity, given the moderately high consumption of fat (i.e. 20%).

Source: Polish Journal of Food and Nutrition Sciences

Authors: Małgorzata Stachoń, E. Fürstenberg, Beata Siriska, Joanna Gadzialska, Joanna Gromadzka-Ostrowska

Language: English

Topic: Diet, Metabolism, and Disease

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $485

OpenAlex ID: W2156819582

FWCI:

Cites: 17

Cited by:

Related to: 10