Work

Leukocytes in Mammary Development and Cancer

Year: 2010

Type: preprint

Abstract: Leukocytes, of both the innate and adaptive lineages, are normal cellular components of all tissues. These important cells not only are critical for regulating normal tissue homeostasis, but also are significant paracrine regulators of all physiologic and pathologic tissue repair processes. This article summarizes recent insights regarding the trophic roles of leukocytes at each stage of mammary gland development and during cancer development, with a focus on Murids and humans.

Source: Cold Spring Harbor Perspectives in Biology

DOI: 10.1101/cshperspect.a003285

Authors: L. M. Coussens, J. W. Pollard

Institutions: University of California, San Francisco, UCSF Helen Diller Family Comprehensive Cancer Center, Albert Einstein College of Medicine

Language: English

Topic: Immune cells in cancer

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: U.S. Department of Defense, National Cancer Institute