APOLIPOPROTEINS AND LIPOPROTEIN (a) IN PATIENTS WITH PREMATURE MYOCARDIAL INFARCTION AND THEIR CHILDREN
Year: 2010
Type: article
Study design: Observational Study
Abstract: INTRODUCTION: A positive family history of premature coronary artery disease can prompt the assessment of children of the family for coronary risk factors like hypertension, obesity and dyslipidemia. This study was performed to determine the relationship between lipoprotein (a), apolipoprotein A1 and B100 in patients with a positive history of premature myocardial infarction and their offspring. methods: This cross-sectional study was conducted on 91 parents and their offspring (91 children). The parents were randomly selected from among patients with premature myocardial infarction hospitalized in the critical care unit of Vali-e-Asr hospital (Birjand, Iran). Lipoprotein (a), apolipoprotein A1 and B100 were measured in both groups. results: Our study showed a significant relationship between lipoprotein (a) levels in parents and their children. High lipoprotein (a) and high apolipoprotein B100 in parents and their children were also significantly related. CONCLUSIONS: We recommend that lipoprotein (a) and apolipoprotein B100 be measured in children with familial history of premature myocardial infarction. Keywords: Premature myocardial infarction, lipoprotein (a), risk factors, offspring, apolipoproteins.
Authors: Azita Fesharak Nia, Fatemeh Tahri
Institution: Birjand University of Medical Sciences
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2157307453