Work

Factors Associated with Immunoglobulin G Subclass Polarization in Naturally Acquired Antibodies to Plasmodium falciparum Merozoite Surface Proteins: a Cross-Sectional Survey in Brazilian Amazonia

Year: 2006

Type: article

Abstract: We investigated immunoglobulin G (IgG) subclass antibody responses to Plasmodium falciparum merozoite surface protein 1 (MSP-1) and MSP-2 in 112 malaria-exposed subjects in Brazil. IgG3 polarization was primarily epitope driven, being little affected by cumulative or current exposure to malaria and not affected by a subject's age and Fcgamma receptor IIA genotype.

Source: Clinical and Vaccine Immunology

DOI: 10.1128/cvi.00095-06

Authors: Kézia K. G. Scopel, Cor J. F. Fontes, Marcelo U. Ferreira, Érika M. Braga

Institutions: Universidade Federal de Minas Gerais, Harvard University, Universidade de São Paulo, Universidade Federal de Mato Grosso

Language: English

Topic: Malaria Research and Control

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2157343027

FWCI: 2.34

Cites: 31

Cited by: 20

Related to: 10