Work

Acetylcholinesterase Inhibition by Flavonoids from Agrimonia pilosa

Year: 2007
Type: article
Abstract: In a bioassay-guided search for acetylcholinesterase (AChE) inhibitors from 180 medicinal plants, an ethyl acetate extract of whole plants of Agrimonia pilosa ledeb yielded tiliroside (1), 3-methoxy quercetin (2), quercitrin (3) and quercetin (4). We report herein for the first time that all four flavonol compounds showed significant inhibitory effects on AChE, particularly quercetin (4), which showed twice the activity of dehydroevodiamine (DHED).
Source: Molecules
Institution: Yonsei University
Language: English
Field: Medicine
Open Access status: gold
Estimated APC paid: $3,258
OpenAlex ID: W2157461655
FWCI: 5.77
Cites: 17
Cited by: 273
Related to: 10