Work

Urine-Based Assays for the Detection of Bladder Cancer

Year: 2009

Type: article

Abstract: Bladder cancer is one of the most prevalent cancers worldwide. Furthermore, nonmuscle invasive bladder cancer has a 70% rate of recurrence, making it a considerable strain to the healthcare system. Patients with bladder cancer require repeat cystoscopic examinations of the bladder to monitor for tumor recurrence. The reason these patients have to undergo these costly, painful, invasive procedures is owing to the absence of accurate urine-based assays to detect the presence of bladder cancer noninvasively. Consequently, the development of a urine-based test to detect bladder cancer would be of tremendous benefit to both patients and healthcare systems. This article reports some of the more prominent urine markers in use today. In addition, the article will highlight some new technologies that are used to investigate novel urinary markers.

Source: Biomarkers in Medicine

DOI: 10.2217/bmm.09.23

Authors: Patrick Villicana, Bryant Whiting, Steve Goodison, Charles J Rosser

Institutions: University of Florida, University of Florida Health Science Center

Language: English

Topic: Bladder and Urothelial Cancer Treatments

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Flight Attendant Medical Research Institute, National Cancer Institute