Work

Mammalian Zinc Transport, Trafficking, and Signals

Year: 2006
Type: review
Abstract: Structural, catalytic, and regulatory functions of zinc in biology continue to be defined. The number of genes coding for proteins with zinc-binding domains is conservatively estimated at >3% of the human genome but possibly is as much as 10% (1, 2). Zinc utilization in abundant, yet diverse, applications illustrates why organisms have evolved specific pathways to homeostatically regulate availability of this essential micronutrient at specific cellular sites through an array of transporters. Animals regulate zinc gain and loss efficiently.
Language: English
Field: Nursing
Open Access status: hybrid
Estimated APC paid: $3,430
OpenAlex ID: W2157810907
FWCI: 4.056
Cites: 65
Cited by: 705
Related to: 10