Work

Are Short Telomeres Predictive of Advanced Cancer?

Year: 2013

Type: article

Abstract: Summary: The combination of variable telomere length in cancer cells and shorter telomere length in cancer-associated stromal cells strongly correlates with progression to prostate cancer metastasis and cancer death. The implication is that telomere length measurements have potential not only as prognostic indicators of prostate cancer outcomes but also as risk stratification enrichment biomarkers for individualized therapeutic interventions. Cancer Discov; 3(10); 1096–8. ©2013 AACR. See related article by Heaphy et al., p. 1130

Source: Cancer Discovery

DOI: 10.1158/2159-8290.cd-13-0506

Author: Jerry W. Shay

Institution: The University of Texas Southwestern Medical Center

Language: English

Topic: Telomeres, Telomerase, and Senescence

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Cancer Institute, National Center for Research Resources