Year: 1999
Type: article
Abstract: The Nuremberg Code recently celebrated its 50th birthday, marking the progress that has been made in ensuring respect for human rights both within and beyond the context of medical research [1].Today, many journal editors will refuse to consider manuscripts that have not undergone formal review by an independent committee, and virtually none will publish results that were procured without the explicit informed consent of the subjects.In one sense, therefore, the bioethics movement of the past several decades seems to have scored a resounding victory.In another sense, however, the rapid pace of medical research and the increasing effectiveness of medical interventions have only intensified the ethical dilemmas that physicians encounter in clinical research.The intensive care environment, in particular, has several characteristics that provide especially difficult challenges to the standard requirements of informed consent for research.I will highlight three features of this environment that may call for innovative or alternative approaches to both study design and the process of informed consent to both respect the rights of the research subject and permit the continued accrual of medical knowledge.
Source: Critical Care
DOI: 10.1186/cc347
Author: Robert D Truog
Institutions: Boston Children's Hospital, Harvard University
Language: English
Topic: Ethics in Clinical Research
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $4,190
OpenAlex ID: W2158310834