Work

The UCSF-FDA TransPortal: A Public Drug Transporter Database

Year: 2012

Type: article

Abstract: Drug transporters play a key role in the absorption, distribution, and elimination of many drugs, and they appear to be important determinants of therapeutic and adverse drug activities. Although a large body of data pertaining to drug transporters is available, there are few databases that inform drug developers, regulatory agencies, and academic scientists about transporters that are important in drug action and disposition. In this article, we inform the scientific community about the UCSF-FDA TransPortal, a new and valuable online resource for research and drug development.

Source: Clinical Pharmacology & Therapeutics

DOI: 10.1038/clpt.2012.44

Authors: K M Morrissey, C C Wen, S J Johns, L Zhang, S-M Huang, K M Giacomini

Institutions: University of California, San Francisco, United States Food and Drug Administration, Center for Drug Evaluation and Research

Language: English

Topic: Drug Transport and Resistance Mechanisms

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of General Medical Sciences