Work

Inhibition of Candida parapsilosis Mitochondrial Respiratory Pathways Enhances Susceptibility to Caspofungin

Year: 2006

Type: article

Abstract: Among the Candida species, Candida parapsilosis has a unique mitochondrial respiratory network. The addition of inhibitors of the respiratory pathways in three clinical isolates of C. parapsilosis with high (> or =2- microg/ml) MICs of caspofungin significantly (fivefold) decreased caspofungin MICs but did not change fluconazole MICs.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.50.2.744-747.2006

Authors: Georgios Chamilos, Russell E. Lewis, Dimitrios P. Kontoyiannis

Institutions: The University of Texas MD Anderson Cancer Center, University of Houston

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2158402055

FWCI: 1.15

Cites: 12

Cited by: 47

Related to: 10