Year: 1998
Type: article
Abstract: ).However,todatelittleatten-tion has been paid to summarising andevaluatingitssignificanceintheassessmentofvaccinequality(definedaseYcacy,eVective-ness, eYciency, safety, and acceptability).Qualityassessmentisimportantasvaccinesareawidelyusedpreventivetechnology,vaccina-tionprogrammesaremostlypubliclyfunded,anddecisionstoimmunisewholepopulationsmustbemadeonthebestavailableevidence,especiallyifsuchpracticeisregulatedbylaw.Additionally the current array of vaccines islikelytobeaugmentedconsiderablyinscopeand variety by new vaccines imposing aresourceburdenonsociety.Suchaburden,setagainstthebackdropofincreasedhealthcarecosts,willnecessitatediscriminationoffundingof preventive programmes. DiscriminationshouldbepartlybasedonthebestavailableevidenceofvaccineeVectivenessandsafety,ofthesocialburdenofthetargetdiseaseandoftheabilityofthevaccinetopreventthatburdendeveloping.
Authors: T Jefferson, V Demicheli, M Pratt
Institutions: Ministry of Defence, Cochrane
Language: English
Subfield: Statistics, Probability and Uncertainty
Field: Decision Sciences
Domain: Social Sciences
Open Access status: bronze
OpenAlex ID: W2158570542