Work

EAACI/GA2LEN guideline: aspirin provocation tests for diagnosis of aspirin hypersensitivity

Year: 2007

Type: review

Abstract: Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most common causes of adverse drug reactions. Majority of them are of the hypersensitivity type. The two frequent clinical presentations of aspirin hypersensitivity are: aspirin-induced bronchial asthma/rhinosinusitis (AIA/R) and aspirin-induced urticaria/angioedema (AIU). The decisive diagnosis is based on provocation tests with aspirin, as the in vitro test does not hold diagnostic value as yet. Detailed protocols of oral, bronchial and nasal aspirin provocation tests are presented. Indications, contraindications for the tests, the rules of drug withdrawal and equipment are reviewed. Patient supervision and interpretations of the tests are proposed.

Source: Allergy

DOI: 10.1111/j.1398-9995.2007.01409.x

Authors: E. Niżankowska‐Mogilnicka, G. Bochenek, L. Mastalerz, M. Świerczyńska, C. Picado, G. Scadding, M. L. Kowalski, M. Setkowicz, J. Ring, K. Brockow, C. Bachert, S. Wöhrl, B. Dahlén, A. Szczeklik

Institutions: Jagiellonian University, Universitat de Barcelona, Royal National Throat Nose and Ear Hospital, Medical University of Lodz, Technical University of Munich, Ghent University, Medical University of Vienna, Karolinska Institutet

Language: English

Topic: Drug-Induced Adverse Reactions

Subfield: Pharmacology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2158692822

FWCI: 2.576

Cites: 35

Cited by: 412

Related to: 10