Work

Clonal Nature of Enterotoxigenic Escherichia coli Serotype O6:H16 Revealed by Randomly Amplified Polymorphic DNA Analysis

Year: 1998

Type: article

Abstract: The genetic relatedness among 29 enterotoxigenic Escherichia coli strains of serotype O6:H16 was investigated by randomly amplified polymorphic DNA (RAPD) analysis. The strains were isolated in different parts of the world, displayed CS1-CS3 or CS2-CS3 profiles, and expressed heat-labile toxin (LT) and heat-stable toxin; a single strain expressed only LT. Ten RAPD types were distinguished and showed significant similarity, having on average 82% of the amplified bands in common. These results indicated that, irrespective of the different geographical origin or virulence factors, these strains belonged to a widespread clonal group.

Source: Journal of Clinical Microbiology

DOI: 10.1128/jcm.36.7.2099-2102.1998

Authors: Ana B. F. Pacheco, Kelen C. Soares, Darcy F. de Almeida, Gloria I. Viboud, Norma Binsztein, Luis C. S. Ferreira

Institutions: Universidade Federal do Rio de Janeiro, Instituto de Biofísica Carlos Chagas Filho, Administración Nacional de Laboratorios e Institutos de Salud

Language: English

Topic: Escherichia coli research studies

Subfield: Endocrinology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Conselho Nacional de Desenvolvimento Científico e Tecnológico, Financiadora de Estudos e Projetos