Work

Effect of a Selective Decontamination of the Digestive Tract Regimen Including Parenteral Cefepime on Establishment of Intestinal Colonization with Vancomycin-Resistant Enterococcus spp. and Klebsiella pneumoniae in Mice

Year: 2006

Type: article

Abstract: In mice, a selective decontamination of the digestive tract regimen consisting of orogastric tobramycin, polymyxin E, and amphotericin B in combination with subcutaneous cefepime inhibited gram-negative bacilli, including Klebsiella pneumoniae, and did not promote vancomycin-resistant Enterococcus spp. (VRE) colonization. However, concurrent administration of subcutaneous ampicillin-sulbactam resulted in promotion of VRE.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.00071-06

Authors: David L. Paterson, Usha Stiefel, Curtis J. Donskey

Institutions: University of Pittsburgh Medical Center, United States Department of Veterans Affairs, Louis Stokes Cleveland VA Medical Center

Language: English

Topic: Nosocomial Infections in ICU

Subfield: Critical Care and Intensive Care Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2159250706

FWCI:

Cites: 14

Cited by: 2

Related to: 10